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Additionally, while my weight, energy levels, and anxiety all improved once I started on thyroid medications, I also had many other symptoms that were not thyroid related, per se, and not responsive to thyroid treatment, like my acid reflux , irritable bowel syndrome , joint pain , and fatigue

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The two axes feed each other in a positive loop that drives protein synthesis, fat oxidation, and connective tissue remodeling beyond what either hormone system achieves independently

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Metformin, a diabetes drug, also lowers B12 absorption

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